Seema Alexander

Seema Alexander believes we’re living through one of the most consequential shifts in business history. And most leaders are still thinking too incrementally about what’s coming.

Her mission is to change that.

An AI Business Futurist, international keynote speaker, serial entrepreneur, and Founder & CEO of Disruptive AI, Seema helps CEOs and business leaders understand the magnitude of this shift, see opportunities others are missing, and rethink how their companies will operate, compete, and create value in the age of intelligence.

For Seema, this mission is personal.

Growing up, she watched her parents build successful businesses, including one of Washington, DC’s first Indian vegetarian restaurants, steps from the White House. She also witnessed what happened when the internet began fundamentally changing how customers discovered, evaluated, and purchased products and services.

That experience sparked a lifelong fascination with a question that would shape her career: Why do some businesses recognize pivotal shifts and reinvent themselves, while others get left behind?

She went on to spend 13 years at Prudential Financial, working across five businesses and contributing to its award-winning brand repositioning, before becoming an entrepreneur and strategic growth advisor to hundreds of companies, from emerging startups to established enterprises.

But it was her early exposure to agentic AI in 2023 that fundamentally changed her perspective on what businesses could become.

She recognized that AI wasn’t simply another technology to adopt. It represented an entirely new set of capabilities for how organizations could think, learn, make decisions, execute work, and create value.

Today, through Disruptive AI, her global keynotes, executive AI fluency experiences, and The AI CEO Podcast, she is helping bridge the growing gap between what’s technologically possible and what business leaders understand and are prepared to do about it.

Her signature Rethink → Reimagine → Rewire™ approach challenges leaders to move beyond incremental improvements and begin building more intelligent, adaptive, and differentiated businesses.

She is also the founder of AI BusinessCon™, the business rewiring conference bringing traditional businesses together with AI-native thinkers, and a former Co-Chair of DC Startup & Tech Week.

And beyond business, Seema is a mother of two daughters who thinks deeply about the world her generation is building for theirs. She believes the choices leaders make today will shape not only the future of industries and economies, but the future of work, opportunity, and human potential.

Her conviction is simple: The future of business isn’t just about what AI can do. It’s about what we choose to build with it.